Nerve sheath myxoma with bidirectional schwannomatous and perineural differentiation.
نویسندگان
چکیده
A case of nerve sheath myxoma occurring in occipital region in 70-yr-old woman is presented. The tumor showed typical lobular and myxoid morphology. Immunohistochemically, it showed unusual coexpression of Schwann cell markers S100 protein and GFAP with perineural cell markers EMA and claudin-1. CD34+ fibroblast-like cells were scarce, and nerve axons were not found in the tumor. Clinical pathology and histogenesis of the lesion are discussed.
منابع مشابه
An Unusual Case of Nerve Sheath Myxoma with Schwannomatous and Perineural Differentiation
Nerve sheath myxoma (NSM) is a rare benign tumour of peripheral nerves. It is seen in middle aged adults with slight female predilection and presents as a slow growing painless mass. The commonest sites are extremities, scalp, back and neck. Microscopically it has a typical morphological appearance. It is multilobulated and is composed of spindle and stellate shaped cells set in an abundant myx...
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عنوان ژورنال:
- Ceskoslovenska patologie
دوره 46 3 شماره
صفحات -
تاریخ انتشار 2010